THE IMPORTANCE AND VALUE OF THE GENOME
The story of our life is imprinted in the genome, then why we don’t look at the genome to unveil the secrets of neurodegenerative diseases. We are living in an era where we can now sequence the whole human genome (>3 billion base pairs) in quick time. The disease programming takes place in the genome, therefore, the genome carries vital information about a disease that we can’t see from the outside, and can guide us in understanding the disease.
We are currently studying Motor Neuron Disease and other NDs at the genomic and sub-genomic levels. Some studies have overlooked the associations between gene expression and its regulation, which we have taken on board as our integrated approach for understanding how genes are regulated by miRNAs. We see the biggest chances of success because of the holistic and in-depth nature of our approach.